A-Lokus Labrador Retriever In Australian Shepherds the disease

In Australian Shepherds the disease was identified between 4 and 19 months of age

❗ Noch kein DogCheck 4

Mutation: TYRP1-Gen

000 genetic markers

A-Lokus Labrador Retriever In Australian Shepherds the diseaseAgouti signal peptide (ASIP) or A Locus is responsible for many different colour patterns in dogs. Specific A Locus allele products can interact with functional MC1R and thus interfere with production of black melanin. Dogs have four different ASIP gene alleles with following dominance hierarchy: Ay > aw > at > a, meaning that the most dominant allele present will be expressed. Genes on A Locus (agouti) are expressed only if a dog on K Locus does not