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Target levels above 30 ng/mL, ideally between 40-60 ng/mL
The significance of this weak binding to IGFBPs is that the compound can exert more pharmacological action in animal subjects since IGFBPs decrease the pharmacological activity of hormones that are strongly bound to it
Thinking one could substitute for the other in a research context would be a catastrophic error in study design
-glutamyl conjugates and N acetyl -glutamyl conjugates Due to the tissue distribution of GT, -glutamyl prodrugs have been mostly developed for kidney applications
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