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Update: This kept getting worse and using a smaller needle didn't help, so I'm going to switch to once-weekly injections and also dilute the drug with significantly less reconstitution solution (20 mg / mL)

Adding cagrilintide mid-cycle: Community protocols add cagrilintide on a tirzepatide injection day so the schedules line up going forward

Over time, obese patients lose roughly 12% of their body weight on Wegovy (semaglutide) and about 18% on Zepbound (tirzepatide, which targets GLP-1 and another gut hormone, GIP.) Diana Thiara, MD, medical director of the UCSF Weight Management Program, says the results can be amazing and life-changing for people with obesity, a condition linked to a host of health risks

Negative reviews, where they exist, tend to focus on medication side effects rather than operational failures, which is a qualitatively different complaint profile than most competitors