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Preclinical studies have also revealed that dual agonists of GLP-1R and glucose-dependent insulinotropic polypeptide receptor (GIPR) have synergistic anti-inflammatory and neuroprotective effects, suggesting the potential advantages of multitargeting strategies (Yuan et al., 2024)

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2 WeightWatchers also still offers its core Points-based programme for people not taking medication, and it can be used alongside the GLP-1 programme