The 2026 reversal, even if partial, corrects some of that damage
HGF/c-Met signaling is a well-established oncogenic pathway: c-Met is amplified or overexpressed in multiple cancers (gastric, lung, renal, hepatocellular) HGF/c-Met activation promotes tumor cell proliferation, survival, invasion, and metastasis c-Met inhibitors are FDA-approved cancer drugs (cabozantinib, crizotinib, capmatinib) A compound that potentiates HGF/c-Met signaling raises theoretical concerns about promoting tumor growth or transformation with chronic use
Neuroprotection Selank : Demonstrates antioxidant effects and supports immune function, protecting neurons from oxidative damage ( 2, 3 )
The conserved disulfide bridgeanalogous to Cys182Cys189 in full-length hGHpotentially confers structural stability by locking the peptide into a bioactive conformation