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1 Introduction Inflammatory bowel disease (IBD), comprising Crohns disease (CD) and ulcerative colitis (UC), is a multifactorial, chronic, immune-mediated inflammatory disorder that affects the gastrointestinal system

When comparing the hair loss status of the four study groups after 9-month, to the baseline, it turned out that on average all three groups that received a treatment, had a reduced hair loss rate, but not the no-treatment control

Tumor risk via p53 pathway interference Mitigate risk by: Careful patient selection: exclude patients with pre-existing active malignancy or high tumour risk (e.g., known p53 mutations, familial cancer syndromes)