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Tromethamine (aka THAM) is a synthetic amino acid that shows up in skincare as a helper ingredient

Initial adjustment period

Here is what happens when NNMT is overactive: Your cells store more fat and burn less energy NAD+ levels drop (a critical molecule for energy production and cellular health) Insulin sensitivity decreases (making it harder to control blood sugar) Inflammation increases in fat tissue Metabolism slows down According to research in PMC, NNMT expression is upregulated in the white adipose tissue of obese and diabetic mice

The inflammation is often the result of hidden infections, exposure to toxic mold, hidden food allergies, and/or stress