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The protein thioredoxin, together with TXNRD1 (or TXNRD3), NADPH, and FAD, constitute the thioredoxin antioxidant system involved in the reduction of antioxidant enzymes (e.g., peroxiredoxins, methionine sulfoxide reductases, and ribonucleotide reductase) and of many oxidation/reduction (redox)-sensitive signaling proteins (9)

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Effect size was presented as odds ratio (OR) with 95% confidence interval (CI)

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In some cases, patients with certain medical histories or conditions may need to consider alternative therapies or modify their treatment approach

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