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Why IGF-1 LR3 is more potent than native IGF-1 Native IGF-1 is largely sequestered in circulation by IGF binding proteins (IGFBPs) a family of six proteins that escort IGF-1 around the body and limit how much is free to engage receptors

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Its purely anecdotal evidence. Doctors also said peptides should not be used as a complete replacement for a healthy lifestyle, and encouraged those interested to prioritize diet, exercise and quality sleep