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The Nature Metabolism study ran for 11 weeks and demonstrated peak effects 35% reduction in white adipose tissue by the endpoint

3-Adrenergic Receptor Modulation Both hGH and AOD9604 increase 3-adrenergic receptor (3-AR) expression in adipose tissue importantly, restoring repressed 3-AR RNA levels in obese mice to levels comparable with those in lean mice

Systemic administration for collagen synthesis research typically falls in the 1mg to 2mg range