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[253] Lutein and zeaxanthin Lutein and zeaxanthin are the only carotenoids found in the human lens and retina, with high concentrations in the macula of the retina, where they serve as both antioxidants and optical filters, safeguarding the retina from the harmful effects of high-energy light, including blue and ultraviolet light

Reduced SAM-to-SAH Ratio A low ratio suggests less effective methylation potential even when a single SAM value appears adequate

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