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Sterile water can be used only for immediate single-dose administrationit contains no preservative, so bacterial contamination risk becomes unacceptable after the first needle puncture

Neuromuscular symptoms are often the first indicators of electrolyte disturbance

For instance, in October 2022, the government of Canada announced a new framework for diabetes in Canada

As a result, most parasitic antigens only induce partial protective immunity, which undoubtedly aggravates the difficulty in finding a qualified vaccine candidate to induce long-term, specific, and effective immune responses ( A compromised innate immunity response hampers parasite elimination in hosts Adaptive immunity presents a significant memory trait, which induces stronger and faster immune responses upon second exposure to pathogens, thus providing long-term protection against infection