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By mimicking the GLP-1 hormone, slowing the digestive process, and stimulating fat oxidation, semaglutide can help patients lose large amounts of belly fat

This polyspecificity distinguishes Melanotan-2 from the next generation of analogs:PT-141 / bremelanotide is MC4R preferential, afamelanotide (Scenesse) is MC1R selective

The severity of MT-1 and MT-2 side effects appears to increase in proportion with the dose

The drugs are intended for people with type 2 diabetes but recently Hollywood celebrities such as Rebel Wilson and Sharon Osbourne have publicly admitted to taking the medication for off-label weight-loss purposes