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In addition, obesity could inhibit hepatic utilization of BCAAs and cause the inactivation of BCKDH by increasing the ratio of BCKDK (BCKDH kinase)/PPM1K (BCKDH dephosphorylase) in hepatocytes

In addition, the presented findings are limited to the curated epitopes that are currently found in the Immune Epitope Database (IEDB, and to 77 different human tissue antigens that were tested for cross-reactivity