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Thus, it is not surprising that GSH (or the [GSH]/[GSSG] ratio) plays a key role in many diseases including cancer, inflammation, Alzheimer's disease, Parkinson's disease, sickle cell anemia, liver disease, cystic fibrosis, AIDS, heart attack, stroke, and diabetes [4, 6] as well as in aging [79]
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We are thankful to Dr Jean Kim and the Human Stem Cell Core at Baylor College of Medicine for mediating the cell transfer, Dr Tobias Dick for Grx1-roGFP2 plasmid, and Drs Vsevolod Belousov, Luke Lavis, and Catherine Goodman for thoughtful discussions
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