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PUF-11 was identified as a strong candidate as it displays similar RNA-binding specificity to FBF and interacts with LST-1 in a large scale yeast two-hybrid screen ( puf-11 and puf-3, have 90% nucleotide identity with each other, and 88% identity at the amino acid level ( puf-3 and puf-11 single mutants, as well as the double mutant, have relatively wild-type progenitor zone sizes, with the double mutant being defective for oogenesis ( puf-11 or puf-3 in an fbf-1 fbf-2 background results in a reduction in GSC proliferation as compared to fbf-1 fbf-2 double mutants ( fbf-1 fbf-2
Free healthcare enhances generalizability, and unique personal identifiers enabled complete linkage across registers, providing full follow-up on suicide and suicide attempts from mortality and hospital data
Its time to test your knowledge of ligand design
Ozempic is the FDA-approved brand name semaglutide which is available for management of T-2 diabetes and Wegovy is the FDA-approved brand name semaglutide available for weight management
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