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FDA prescribing information for some GLP-1 receptor agonists (particularly those approved for weight management) includes recommendations to monitor heart rate at regular intervals and consider discontinuation for sustained increases in resting heart rate

This symptom may be inconvenient or concerning, prompting patients to ask whether semaglutide is causing the problem, if its a sign that the medication is working, or whether it might be an indicator of an underlying issue

Regulatory exclusivity is a statutory right granted by the FDA as a policy incentive for specific types of drug development

According to study results, GLP-1RA use was associated with significantly higher rates of retained gastric content (OR = 5.56