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Despite the high overall yield in the described solid phase approach, it has several drawbacks for the scale-up process such as the application of the highly toxic and corrosive hydrogen fluoride for cleavage of the peptide from the resin, low loading (0.300.35 mmol/g of resin) proved necessary for successful on-resin cyclization, and the use of excess amounts of reagents (3-fold of DIC, 2.4-fold of HOBt, etc.) on each step
These injectable biomaterials could potentially replace the nucleus pulposus while promoting surrounding tissue repair
A meal with healthy fat is the difference between something that passes through quickly and something that actually sticks with you
Effects of high MG levels on the body : Increased amounts of MG lead to problems with mitochondrial function and cause oxidative stress, which disrupts neuron activity
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