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Insulin resistance, a pathology closely associated with obesity, sarcopenia, and chronic low-grade inflammation -including age-related inflammaging- represents another key target of GLP-1RA actions

Rinvoq (upadacitinib) Disease area(s): Immunology Manufacturer(s): AbbVie 2024 Sales (USD): $5.97 billion Why it sold so well: AbbVies Rinvoq experienced substantial sales growth in 2024, with global revenues increasing by 46.2% year-over-year to $1.83 billion in the fourth quarter alone

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It may support muscle development and response to training in exercising horses