Although the comparison between 34 hr and 58 hr showed no differences in most metabolites except butyrates and OA, we also noticed that some metabolites peaked in 34 hr, while other metabolite kept increasing until 58 hr (cis-aconitate, succinate, nicotinamide (Fig
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These observations indicate that the principal challenge is no longer identifying additional flavonoid-associated genes or metabolites, but determining which regulatory interactions consistently govern metabolic behavior across diverse stress combinations