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HPLC-purified for high analytical purity, it is suitable for investigating neuropeptide activity and biochemical mechanisms

Epidermal PIH may resolve better and faster than dermal PIH where melanin accumulates in long-lived melanophages [27]. Melasma is also a chronic acquired hypermelanosis which involves increased melanin levels in the epidermis and/or dermis [28,29,30]. It manifests as bilateral dark or grayish-brown macules, more particularly located on the face

doi: 10.1007/s11010-011-1217-3 115 MontjeanDMnzoYBenkhalifaMCohenMBellocSCohen-BacriePet al

Si parla di cambiamenti visibili nellarco di 4-8 settimane, con un plateau attorno alle 12