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All animals were treated humanely, and all studies were carried out in accordance with good laboratory practice (GLP) (China Food and Drug Administration, CFDA) guidelines for nonclinical laboratory studies of drugs issued by the National Scientific and Technological Committee of the Peoples Republic of China

Abstract Fibromyalgia (FM) is increasingly recognized as a disorder driven by oxidative stress, mitochondrial dysfunction, and neuroinflammation, contributing to pain sensitization and fatigue

B12 is an essential vitamin, playing a crucial role in the body including converting food into energy, the production of red blood cells to carry oxygen around the body, make DNA, balance hormones and the maintenance of a healthy nervous system

These findings suggest potential relevance not just for longevity, but also for regenerative medicine and age-related tissue repair