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Additional benefits included reductions in body mass index (BMI), blood pressure levels, HbA1c, and fasting blood glucose, observed after a minimum of six months of clinical follow-up ( Notably, the study by Marfellas et al

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Chronic illness, like diabetes, can also interfere, partly because diabetes is associated with higher rates of obesity and PCOS, which are both factors causing irregular periods

Other interactions can increase side effects or make them more severe