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The downside is that the population may not be representative of the overall population since it is made of veterans (for example, 95% male)

The medical community has evolved in its understanding of obesity treatment

Biochem Biophys Res Commun 324:9297 Lindsay JR, Duffy NA, McKillop AM et al (2005) Inhibition of dipeptidyl peptidase IV activity by oral metformin in type 2 diabetes