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[1] [2] EC 50 values should always be read in the context of the assay that produced them

Incidence of severe hypoglycemia was 1% b Hypoglycemia was more frequent when RYBELSUS was used in combination with insulin secretagogues (eg, sulfonylurea) or insulin - Patients may require a lower dose of the secretagogue or insulin to reduce the risk of hypoglycemia in this setting A cardiovascular outcomes trial (CVOT) compared RYBELSUS added to standard of care vs placebo added to standard of care Primary endpoint was the time to first occurrence of a 3-part composite outcome of major adverse cardiovascular events (MACE), which included cardiovascular death, nonfatal myocardial infarction, and nonfatal stroke The total number of primary component MACE endpoints was 137 (61 [3.8%] with RYBELSUS and 76 [4.8%] with placebo) CV=cardiovascular

Many patients suffering from a B12 deficiency visit their GP complaining of tiredness and fatigue

They tell me it makes them nauseous and sick, but theyre on it because their parents had an issue with their weight and put them on it