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Executive Director Shabbir Imber Safdar argued that the committee's decision is "a serious setback for patient safety," warning that it could legitimize compounds lacking adequate clinical evidence and increase the spread of potentially unsafe products through wellness clinics, medical spas, and online platforms

20(S)-hydroxycholesterol inhibits PPAR expression and adipogenic differentiation of bone marrow stromal cells through a hedgehog-dependent mechanism

Though adverse effects havent been widely reported, side effects can vary based on individual health

Investigators also collected serial blood samples to track shifts in lipids, C-reactive protein, and liver enzymes, providing a broader picture of metabolic health