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Assay: GSH/GSSG in rat brain hippocampus tissue

Thereafter, we observed increased expression of cell death marker cleaved-caspase 3 upon sertraline as monotherapy in NCI-H125, NCI-H1975, NCI-H1299 and HCC15 cell lines, and the combination therapy in NCI-H125, NCI-H520, NCI-H1975, NCI-H1299 and HCC15 cell lines, highlighting the partial cytotoxic effect of sertraline and combination therapy (Supplementary Fig

Heneka MT, Carson MJ, El Khoury J, Landreth GE, Brosseron F, Feinstein DL, et al

However, stronger and faster results also come with a greater risk of testosterone suppression, fertility problems, cardiovascular strain, liver concerns, mood changes and other systemic effects