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10.1111/j.1369-1600.2006.00041.x Addict Biol
Singh KJ, Kaur J
Mechanism of Action Inhibits Nicotinamide N-Methyltransferase (NNMT) Increases intracellular nicotinamide and NAD levels Improves mitochondrial efficiency and energy metabolism Supports lipolysis and fat oxidation Reduces adipocyte (fat cell) growth and proliferation Modulates inflammatory pathways and insulin signaling These effects may lead to enhanced fat metabolism, better blood sugar regulation, improved endurance, and a general increase in metabolic flexibility
It represents only the C-terminal fragment rather than the full-length hormone, which is why it is examined as a structurally distinct research compound in comparative studies
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