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Among them, the glutamate produced by the decomposition of glutamine via GLS not only provides the raw material for the synthesis of GSH but is also further metabolized into -ketoglutarate (-KG) in the mitochondria under the action of glutamate dehydrogenase (GLUD1) or transaminases and then enters the tricarboxylic acid cycle to produce ATP [29]
54 At a concentration of 10 mM, GSH had minimal effects on bacterial growth or biofilm disruption
The contributory role of gut microbiota in cardiovascular disease
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