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While GLP-1RAs are widely used for glycaemic control and have demonstrated cardiovascular and renal benefits, emerging evidence suggests they may also exert neuroprotective effects
There are insufficient high-quality randomised controlled trials to support their use for weight loss
Retatrutide is a new weight loss treatment that targets multiple hormone pathways related to weight regulation
Whether GLP-1 medications exacerbate those effects is an important unanswered question that future studies need to address
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