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If youre severely deficient, your provider may recommend more frequent injections at firstoften once per week before switching to monthly maintenance doses

Higher doses may increase gastrointestinal side effects without improving outcomes

Baseline and interval laboratory monitoring should include: fasting glucose and HbA1c (tirzepatide can cause hypoglycemia in non-diabetic subjects if caloric intake drops too low), lipase and amylase (pancreatitis risk with GLP-1 agonists), liver function tests (AST, ALT, bilirubin), and thyroid panel (TSH, free T3, free T4)

Tesamorelin is a synthetic GHRH analog specifically studied and FDAapproved for reducing excess abdominal fat in HIV-associated lipodystrophy, with strong data on visceral fat reduction