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According to FDA prescribing information, gastrointestinal side effects are typically most pronounced during dose initiation and escalation, and they often diminish over time as the body adapts to the medication

After washing in PBS, primary antibodies (IgM-PE BioLegend 406507, IgD-APC BioLegend 405713, MARCO Santa Cruz sc-65353/ anti-rat PE Abcam ab97058 and Siglec-1 Biolegend 142417) diluted in PBS 10% FCS were incubated overnight at 4 C

Your dosing schedule, medication volume, or support protocols will be fine-tuned to completely minimize side effects and optimize cellular comfort

Expert Review of Neurotherapeutics