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However, patients with a family history of medullary thyroid cancer or those taking insulin should not use tirzepatide
The NIH National Center for Complementary and Integrative Health notes that weight effects appeared mainly at doses above 1 gram per day taken for more than 8 weeks
This can be a sign of contamination or that the peptide has been damaged
The medication's active window spans approximately seven days, after which your body begins metabolizing the compound and its effects gradually decrease
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![Mechanism of action of GLP-1 [25]](https://www.researchgate.net/publication/256289222/figure/fig1/AS:614177232142337@1523442671231/Mechanism-of-action-of-GLP-1-25.png)
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