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Furthermore, L-carnitine is effective for chest pain, heart failure, kidney failure, hyperlipidemia (having high levels of cholesterol or lipids in the blood), male infertility, swelling of the heart, toxic side effects caused by valproic acid, and polycystic ovary syndrome

In addition, COX-2, which is encoded by prostaglandin-endoperoxide synthase (PTGS2), converts AA to multiple prostaglandins, including prostaglandin E2 (PGE2), which is also involved in inflammation

While this risk has not been confirmed in humans, it remains a concern for individuals with a personal or family history of thyroid disease

Establishment of K7M2-Luc orthotopic osteosarcoma mouse model and therapeutic effect evaluation Tumor model establishment To establish orthotopic model, K7M2 cells (3 10 6 cells/well) were dispersed in PBS buffer and implanted into right tibia of BALB/c mice