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When all 56,004 participants from all 7 trials were analyzed together, primary and secondary endpoints of death from cardiovascular causes (fatal or nonfatal stroke, fatal or nonfatal MI) remained significant, albeit modest
[15] Afamelanotide was approved by the FDA in 2019
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Notably, HBV-DNA clearance rates were significantly higher in the observation group at all measured time points, reaching 68.89% clearance at 48 weeks, compared to 42.22% in the control group
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