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However, patients taking multiple antihypertensive medications should have their blood pressure monitored regularly, as excessive lowering could potentially cause symptomatic hypotension, particularly in elderly patients or those with autonomic dysfunction

People who expect instant results often quit early

Several case reports have described individual patients developing or experiencing worsening depression temporally associated with semaglutide use

However, the time it takes for these mechanisms to translate into measurable improvements varies considerably between individuals and depends on the specific outcome being measured