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The methionine cycle metabolites adjust very rapidly to the decreased methionine input reaching new steady states within a few hours
Although a low concentration of homocysteine in its reduced form behaves as a pro-oxidant, in high concentration, homocysteine, like other thiols, presents a free-radical scavenger activity (Munday, 1989)
Though not dangerous, these symptoms can be uncomfortable and may persist with continued high-dose usage
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