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The pathophysiological mechanisms that statins attack are identical
In db/db mice, exendin-4 (EX-4) significantly suppressed the overexpression of pyroptosis-related proteinsincluding ASC, caspase-1, IL-1, and GSDMD
Diabetologia 59:13721375 Liang Y, Osborne MC, Monia BP et al (2004) Reduction in glucagon receptor expression by an antisense oligonucleotide ameliorates diabetic syndrome in db / db mice
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