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Note also that GSH inhibits both GCL and GS, so it is not clear by inspection of the diagram what the effect of raising the activities of GCL and GPX will be
Yu HH, Joubran R, Asmi M, Law T, Spencer A, Jouma M, and Rifai N (2000)
2023, found increased risk for specific cancers including hematological, connective tissue, and pancreatic malignancies but no clear increased risk for prostate, hepatobiliary, or skin cancers, and mixed findings on breast cancer specifically