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Patients with kidney disease (CKD) should exercise particular caution with vitamin D3, as impaired kidneys have reduced ability to hydroxylate D3 and are more susceptible to hypercalcaemia
[1] That is a real, high-tier evidence base for a specific disease endpoint, and it is why the drug reached the market
GLP-1 receptor activation reduces antral motility, alters pyloric function, slows gastric transit, and contributes to nausea, early satiety, bloating, and postprandial fullness in susceptible patients
Cortisol level to exclude adrenal insufficiency: Generally, a stressed, hypoglycemic patient should have elevated cortisol levels
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