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On the other hand, the icv administration of GLP-2 to mice and rats produced a marked decrease in food intake but not in water ingestion [43]

Phase II Detoxification : This tripeptide serves as a cofactor for glutathione S-transferases, conjugating with xenobiotics and metabolic waste products to facilitate their elimination through bile and urine pathways

Bylece hem kas kazanm hem de ya yakm bir arada salanr

This behavioral disadvantage, however, was significantly reduced in the ICV-STZ rats on berberine supplementation, indicating that berberine was able to preserve memory and learning in rats that would have otherwise been subjected to the neurocognitive deficits associated with Alzheimers disease