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Vitamin B12 deficiency is more prevalent than many people realise: Around 6% of the UK population has B12 deficiency This rises to approximately 20% in those over 60 An estimated 1 in 10 people in the UK may have inadequate B12 levels 6% of men and 10% of women aged 19-64 have low serum B12 concentrations Among women of reproductive age (19-49), 11% have low B12 Interestingly, research suggests that deficiency is often due to absorption problems rather than dietary intake
For example, for measuring length we have training sessions where the fieldworkers and a gold standard measure each child twice
Vitamin B12 requires an intrinsic factor-mediated active transport for absorption, therefore, lack of or inhibition of intrinsic factor results in pernicious anemia
When investigating elevated B12, additional tests such as active B12 (holotranscobalamin), methylmalonic acid, and homocysteine may help clarify true B12 status
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