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Clin Chest Med

Once patients get to mid to high doses of 8 to 12 mg, costs rise precipitously

The significant increase in risk is driven primarily by enteric hyperoxaluria, reduced urinary citrate, and lower urine volume. As clinicians continue to monitor outcomes, Wood emphasized that hydration remains one of the simplest and most effective ways for GLP1 users, especially those with a history of stones, to support kidney health.

Semaglutides anti-inflammatory action might play a part in an effect that recently made headlines: the drug provides strong protection against cardiovascular disease in people with obesity