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In summary, an increasing number of clinical studies support that GLP-1 RAs can improve the clinical and pathological changes in PD, providing long-term benefits for patients cognitive and motor symptoms

[1] This means patients can use any of the approved sites without needing to adjust their dose or timing

Long interested in Holst's work, in 1990 Novo Nordisk recruited his colleague Schwartz to develop small molecules able to activate the GLP receptor in the pancreas (Molteni, Chen)