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After single IV administration, the t 1/2 and AUC 0t of BPC157 in dogs were 5.27 min and 76.4 30.2 ng min/ml

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Stanaway JD, Reiner RC, Blacker BF, Goldberg EM, Khalil IA, Troeger CE, Andrews JR, Bhutta ZA, Crump JA, Im J, Marks F (2019) The global burden of typhoid and paratyphoid fevers: a systematic analysis for the Global Burden of Disease Study 2017

While regulation of iron metabolism-related proteins or the use of iron chelators can reduce intracellular labile Fe 2+ levels and inhibit ferroptosis, current chelators lack tissue and cellular specificity and may interfere with neurophysiological functions, thereby limiting their clinical applicability