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However, the known contraindications that clinicians must observe include personal or family history of medullary thyroid carcinoma and multiple endocrine neoplasia syndrome type 2 (MEN 2), both related to thyroid C-cell concerns identified in rodent studies
(Wolffenbuttel BHR, Wouters HJCM, Heiner-Fokkema MR, van der Klauw MM
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