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Recent studies show that GLP-1(936) can activate the inhibitory G protein (Gi/o), leading to the translocation of secretory granules (SG) beneath the cell membrane, thereby inhibiting glucagon secretion.241 This mechanism is unaffected by genetic or pharmaceutical inhibition of GLP-1R, but it is sensitive to pertussis toxin
W., Murphy, M
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A nivel heptico, disminuye el nivel de esteatosis, de VLDL y ApoB100 y la produccin de glucosa, mientras que, a nivel cerebral, los GLP-1 disminuyen el apetito y la ingesta de lquidos
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