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Notably, completed and ongoing studies such as NCT06475586, NCT06937060, NCT06588296, and NCT06864026 are investigating semaglutide in patients with PsO and comorbid metabolic conditions, or tirzepatide (in PsA settings), assessing dermatologic outcomes and inflammatory or metabolic markers (78, 79)

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The most common (water retention, tingling, injection site reactions) resolve on their own or with dose adjustments

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