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Avoid anything too abrasive though, as this can cause damage to your skin in the long run

Lima Giacobbo B, Doorduin J, Klein HC et al (2019) Brain-Derived Neurotrophic Factor in Brain Disorders: Focus on Neuroinflammation

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Heat shock proteins such as HSP70 and HSP90 prevent protein denaturation during freezing, while antioxidant enzymes such as SOD and catalase protect against oxidative stress (160, 161)