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If you miss a dose, follow the specific instructions provided with your medication, which vary by agent
Use reliable contraception while taking this medication, and discuss family planning with your provider
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At the tissue level, in vitro work using isolated pancreatic islets has characterised tirzepatide's effect on glucose-stimulated insulin secretion (GSIS), with multiple groups reporting that the dual-agonist produces greater cAMP accumulation in -cells than mono-agonists at matched concentrations
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